Lichen sclerosus
Conditions
Interventions
Not applicable.
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Inclusion criteria
Inclusion criteria: Female, aged 21 years or younger, diagnosed with anogenital lichen sclerosus.
Exclusion criteria
Exclusion criteria: Only extragenital presentation of LS (no anogenital involvement). In addition, visits during which the patient is pregnant will be excluded from analysis, although the patient will remain enrolled in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters include patient characteristics, symptoms, clinical presentation and management of anogenital LS in girls. The primary endpoint is the difference in these parameters between the premenarche group and the postmenarche group. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary study parameters include the persistence of anogenital LS after menarche and the disease course in patients with persistent anogenital LS.Menarcheal status is determined at the time of LS diagnosis. If the age of menarche/menarcheal status is unknown, patients will be categorized based on the average age of menarche in the Netherlands. Patients younger than this age will be classified as premenarcheal, while patients at this age or older will be classified as postmenarcheal. The secondary endpoint is the proportion of girls with persistent anogenital LS after menarche and an overview of the course of disease in these patients with persistent anogenital LS at specific time points (first visit, second visit, first visit after menarche and most recent visit). | — |
Countries
Netherlands
Contacts
Public ContactW. Dorp
Erasmus MC, Universitair Medisch Centrum Rotterdam
Outcome results
None listed