Aneurysm
Conditions
Interventions
No product under research or intervention. The study concerns a biobank. 
Sponsors
Maastricht Universitair Medisch Centrum +
Eligibility
Inclusion criteria
Inclusion criteria: Patients with an arterial aneurysm (thoracic aortic aneurysm/abdominal aortic aneurysm/intracranial aneurysm).
Exclusion criteria
Exclusion criteria: Mentally incapacitated patients, patients < 18 years old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Given the exploratory and long-term nature of this biobank, specific outcome measures will depend on the individual research questions addressed in future studies. However, the biobank is designed to support a wide range of potential outcome measures across various domains, including: Biological and molecular outcomes: Identification of biomarkers (e.g., proteins, gene variants, RNA expression patterns) associated with aneurysm presence, growth, or rupture risk.Genetic outcomes: Associations between genetic variants and aneurysm subtypes, progression, or familial predisposition (e.g., via genome-wide association studies or sequencing approaches).Clinical outcomes: Correlations between clinical characteristics (e.g., age, sex, comorbidities, medication use) and aneurysm progression or treatment response.Imaging or anatomical outcomes: Aneurysm size, growth rate, morphology, or rupture incidence over time.Therapeutic outcomes (translational research): Response to candidate drug targets in ex vivo models, or identification of mechanisms underlying treatment resistance or efficacy. | — |
Countries
Netherlands
Contacts
Public ContactBME Mees
Maastricht Universitair Medisch Centrum +
Outcome results
None listed