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DuTOC

Prospective data collection initiative on Thoracic Malignancies - a prospective observational cohort study – - DuTOC

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON57887
Enrollment
12000
Registered
2025-02-03
Start date
2025-08-15
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Malignancy, Lung cancer, lung tumor, Lung carcinoma, SCLC (small cell lung cancer), NSCLC (non-small cell lung cancer), Adenocarcinoma, Squamous cell carcinoma, Large cell carcinoma, Thymus cancer, Mesothelioma

Interventions

None listed

Sponsors

Stichting NVALT-studies
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age = 18 years;Histo/cytopathological proof of a thoracic malignancy, or a strong suspicion (after imaging and multidisciplinary board);Informed consent for longitudinal observational data collection;

Exclusion criteria

Exclusion criteria: Mentally challenged patients that are unable to provide conscientious informed consent as determined by the investigator.Inability to provide a written or electronic informed consent.

Design outcomes

Primary

MeasureTime frame
Clinical parameters as comprehensive as possible: medical history, co-morbidities, medication use, basic physical examination, laboratory results, imaging results, pathology results, tumor characteristics, treatment, treatment outcomes, hospital stays, interventions, pharmaco-economic data and adverse events. Clinical endpoints: overall survival and if available treatment response, disease-free survival, progression-free survival, overall survival and grade 3/4 (serious) adverse events. Follow up treatments in case of progressive or recurrent disease. Patient reported outcomes: health related quality of life, work participation and work ability. Biobanking of blood and (tumor) tissue and storage of imaging.

Countries

Netherlands

Contacts

Public ContactW.K. Jong

Universitair Medisch Centrum Utrecht

dutoc@umcutrecht.nl+31 88 75 561 80

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)