mesenteric ischemia
Conditions
Interventions
Intervention: patients get to drink a deuterated glucose solution in water and high caloric  
chocolate milk (total energy intake 600 kcal) after which they undergo an MRI and DMI scans at 7 Tesla.
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with clinically proven chronic mesenteric ischemia that are scheduled for (endo)vascular surgery * 18 =< age =< 80 * Ability and willing to give informed consent * Ability to follow test instructions * Sufficient understanding of the Dutch language
Exclusion criteria
Exclusion criteria: Contra-indications to MRI examination according to 7T MRI screening guideline of the UMC Utrecht, including not being able to fit in the 7T MRIAllergic to milkAcute Mesenteric Ischemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are 3D DMI measurements of deuterated glucose during gastric emptying, intestinal uptake (and partial conversion to lactate) as becomes visible in the portal vein and liver of patients suspected for CMI. A measured signal to noise ratio = 3 of lactate in the portal vein of these patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ratio of deuterated lactate to glucose in the portal vein. | — |
Countries
Netherlands
Contacts
Public Contactwjm Kemp
Universitair Medisch Centrum Utrecht
Outcome results
None listed