Burn injury, burns Burns
Conditions
Interventions
None listed
Sponsors
Vereniging Samenwerkende Brandwondencentra Nederland
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: aged 18-67 yearsadmitted to Burn Centre Groningen, Martini Hospital, or Burn Centre Rotterdam, Maasstad Hospital, with acute burns (wounds still open) covering =5% TBSA at the time of admission and/or a length of stay of =1 weekdischarged from the burn centre between 6 weeks and 12 months before entering the study
Exclusion criteria
Exclusion criteria: extensive (pre-existing) morbidity affecting cardiorespiratory fitness that is unrelated to the burn injuryinsufficiently proficient in Dutch or English to the extent that clear communication is not possiblepresence of contra-indications for maximal exercise according to the Physical Activity Readiness Questionnaire (PAR-Q)inability to cyclefacial burns that impede wearing a breath-analysis face mask
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| From CPET Absolute oxygen uptake at peak exercise (V?O2peak in ml/min)From SRT Absolute work rate at peak exercise (WRpeak in W) | — |
Secondary
| Measure | Time frame |
|---|---|
| Participant characteristicsAge (years)Sex (male/female)Body height (cm)Body mass (kg)Waist and hip circumference (cm)Body fat (%)Fat free mass (FFM in kg)Body Mass Index (BMI in kg/m2)Smoking behaviour (package years)Physical Activity (SQUASH)Pain (PROMIS Pain Intensity)Physical Functioning (PROMIS SF Physical Functioning 8b)Perceived benefits and barriers to exercise: Exercise Benefits/Barriers Scale (EBBS)Difference in physical activity compared to pre-burn Socioeconomic state (based on four numbers of postal code) Burn-specific parameters%TBSA burned%TBSA full thickness burnsNumber of surgeriesTime post burn (days)Time post discharge (days)Length of hospital stay (days)Body location of burnsEtiologyTime on mechanical ventilation (days)Inhalation injury (yes/no)Abbreviated Burn Severity Index (ABSI) an index to indicate a patients’ burn severity based on sex, age, full thickness burns, inhalation injury and %TBSA.43 Parameters from electrocardiogram (ECG)Resting heart rate (bpm) Parameters from blood pressure (BP) measurements:Blood pressure at rest (mmHg) Parameters from spirometryTidal volume (Vt in L)Vital capacity (VC in L)Forced vital capacity (FVC in L)Forced expiratory volume in one second (FEV1 in L)Tiffeneau Index (FEV1/VC)Maximal Voluntary Ventilation (MVV in L/min) Parameters from CPETWasserman nine-panel plotOxygen uptake at peak exercise relative to body mass (V?O2peak in ml/kg/min)Oxygen uptake at peak exercise relative to fat-free mass (V?O2peak in ml/kg/min)Absolute work rate at peak exercise (WRpeak in W)Relative work rate at peak exercise (WRpeak in W/kg)Oxygen uptake (V?O2 in ml/min/kg), heart rate (HR in bpm), work rate (WR in W) at the first ventilatory threshold (VT1) Oxygen uptake (V?O2 in ml/min/kg), heart rate (HR in bpm), work rate (WR in W) at the second ventilatory threshold (VT2) Respiratory exchange ratio (RER) at peak exercise (RERpeak)Heart rate at rest (HRrest in bpm) and at peak e | — |
Countries
Netherlands
Contacts
Public ContactM.K. Nieuwenhuis
Vereniging Samenwerkende Brandwondencentra Nederland
Outcome results
None listed