Acute Myocardial Infarction Related Cardiogenic Shock (AMICS) Acute pumpfailure
Conditions
Interventions
MRI of the brainMontreal Cognitive AssessmentAmsterdam IADL questionnaireInformant Questionnaire on Cognitive Decline in the Elderly (IQCODE) 
EuroQol-5D, including EuroQol Visual Analog ScaleGeriatric Depression Scale 
Starkstein Apathy Scale 
Hospital anxiety and Depression Scale (HADS) 
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: • Hospitalised for AMICS approximately 2 (1-3) years ago • Age 18-75 years • Able to give informed consent • Knowledge of Dutch language • 30/60 patients must have been treated with Impella, VA-ECMO or both. AMI (no CS) Control cohort (n=30) • Hospitalised for AMI without CS approximately 2 (1-3) years • Age 18-75 years • Able to give informed consent • Knowledge of Dutch language
Exclusion criteria
Exclusion criteria: • MRI incompatibility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive impairment Total and gray matter volume and number and volume of white matter hyperintensities measured on MRI | — |
Secondary
| Measure | Time frame |
|---|---|
| • Total cerebrospinal fluid (CSF) volume (mL) • White matter tract damage • Cerebral blood flow (CBF) (gray matter, hippocampus) (mL/100g/min) • Locus Coeruleus contrast ratio | — |
Countries
Netherlands
Contacts
Public ContactJ.P.S. Henriques
Amsterdam UMC
Outcome results
None listed