Geen specifieke aandoening. We zijn benieuwd of lycopeen als een life style compliance marker zou kunnen dienen. Not applicable.
Conditions
Interventions
Oral food supplement tablet 40 mg lycopene once, versus oral soup of cooked
tomatoes equivalent to 40 mg lycopene content. In addition, the participants*
habitual diet and actual food intake during
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Male; • Healthy; • 18-75 yrs old.
Exclusion criteria
Exclusion criteria: • Allergic for tomatoes; • Any gastrointestinal disorder within 3 months prior to the intervention; • Recent medication or supplement use; • Recent substantial change in weight; • Adherence to a specific diet (e.g., vegan); • Using recreational drugs more than once a month; • Smoking and excessive alcohol consumption (>10 standardized glasses a week). • Risk of a dependency situation with the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Raise of plasma lycopene concentration in absolute (ng/ml) and relative (percentage of T0-value) after single lycopene intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Optimal time point of lycopene concentration response after single dietary intervention (hours, days). 2. Influence of prior food consumption on plasma lycopene levels before and after lycopene interventions, as measured by dietary questionnaires. | — |
Countries
Netherlands
Outcome results
None listed