thrombocytopenia low platelet count
Conditions
Interventions
None listed
Sponsors
Franciscus
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Patients with suspected isolated platelet count <150 x 10^9/L (anemia of chronic disease allowed) - Age = 18 years - Written informed consent
Exclusion criteria
Exclusion criteria: - Patients with leukocytopenia, leukocytosis, anemia or erythrocytosis during initial blood test (anemia of chronic disease allowed) - Patients with pseudothrombocytopenia - Pregnant patients - Platelet transfusions in the preceding 48 h before blood sample collection - Patients with unclear diagnosis after the inclusion period - Patients with a platelet count <3*10^9/L
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint will be to validate the specificity of 100% for peripheral thrombocytopenia of an IPF cut-off value of 13% or, if the specificity is not 100%, establishment of a novel cut-off value at which the specificity is 100%. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints will be the correlation between IPF and TPO and establishment of the added value of TPO in the diagnosis of isolated thrombocytopenias with an IPF between the lower and upper cut-off. | — |
Countries
Netherlands
Contacts
Public ContactR.E.M. Verstegen
Franciscus
Outcome results
None listed