Prognostic IntraOperative biomarkers ideNtification in tumor rElatEd suRgery

Prognostic IntraOperative biomarkers ideNtification in tumor rElatEd suRgery - PIONEER

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57654

Enrollment

Registered

2024-09-13

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain tumor glioma braintumor

Interventions

Neuropixel brain recordings

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Age between >18 yrs and

Exclusion criteria

Exclusion criteria: • Psychiatric history, use of psychiatric medication. • Previous brain tumour surgery or radiotherapy. • Severe aphasia or dysphasia. • Patient has pacemaker or other implanted electrical device such as vagal nerve stimulator or other. • Inability to give consent.

Design outcomes

Primary

Measure	Time frame
Primary endpoint: Feasibility of Neuropixels Probe recordings during glioma surgeries.	—

Secondary

Measure	Time frame
Secondary endpoint: Suitability of using intra-operative single-cell recordings to identify prognostic biomarkers for disease progression	—

Countries

Netherlands

Contacts

Public ContactA.J.P.E. Vincent

Erasmus MC, Universitair Medisch Centrum Rotterdam

k.vanderkuil@erasmusmc.nl0641078801

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)