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DNA-analysis of bacteria in prosthesis and implant infections after hip surgery.

Whole genome comparison of bacterial species between prosthetic joint infections in hip surgery and patients’ preoperative microbiome - Sap-study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON57605
Enrollment
400
Registered
2025-02-24
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prosthetic Joint Infections (PJI)

Interventions

&nbsp
Acute or elective hip surgery with the implantation of fixative or prosthetic material.&nbsp

Sponsors

Deventer Ziekenhuis
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria:  Patients must undergo an elective or emergency hip surgery with the implantation of fixative or prosthetic material.   

Exclusion criteria

Exclusion criteria:  Patients that are younger than 18 years old 

Design outcomes

Primary

MeasureTime frame
Patients that have a clinically high suspicion of a postoperative infection or proven postoperative infection within 60 days after surgery. The preoperative swabs of these patients will be cultured in order to sequence the microorganisms and compare them with the pathogen that is swabbed from the infection site, at the time of infection. 

Secondary

MeasureTime frame
Patient characteristics, such as BMI, age, and gender, patient medical history, comorbidities, and current use of medication.Timespan between surgery and development of PJI;Antimicrobial resistant profile of cultured microorganisms.

Countries

Netherlands

Contacts

Public ContactJ.B. van Praagh

Deventer Ziekenhuis

heelkunde@dz.nl0570535060

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Feb 7, 2026