Liver transplantation
Conditions
Interventions
None listed
Sponsors
Universitair Ziekenhuis Gent
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age >= 18 years* Consulted the department of Gastroenterology and Hepatology* Diagnosis of end-stage liver disease, primary hepatic malignancy meeting the AFP model criteria for liver transplantation, or acute liver failure Eligible for liver transplantation and/or active on the waiting list for liver transplantation* Ability to comply with protocol-specified evaluations and scheduled visits* Be able to read and write Understand the patient information
Exclusion criteria
Exclusion criteria: Transplantation of multiple organs that do not include the liver, eg. Combined heart and lung transplantation - subjects who do not fulfill the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary end points of the study are graft loss and death at 3 months after liver transplantation. ** | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints are graft and overall survival at 12 months and 3 year after liver transplantation. The prognostic value of a serum glycomics biomarker for graft and overall survival at 12 months and 3 years after liver transplantation, to study the value of repeated glycomic measurements after liver transplantation and the optimal time-point of biomarker measurement. n the subset of patients receiving a liver transplantation for HCC: HCC recurrence. The predictive value of a serum glycomics biomarker determined before liver transplantation for HCC recurrence, liver-related death, and overall death. The predictive value of a serum glycomics biomarker as marker of early recurrence in patients receiving liver transplantation for HCC when determined during follow up after liver transplantation* | — |
Countries
Netherlands
Outcome results
None listed