MicroCrit

Microcirculation assessment and monitoring in the critically ill patient - Microcirculation assessment and monitoring in the critically ill patient.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57528

Enrollment

200

Registered

2025-05-01

Start date

2025-06-01

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

microcirculation, blood supply organs and tissues, tissue perfusion, tissue oxygenation

Interventions

non-applicable

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults age (age = 18 years) admitted to the ICU

Exclusion criteria

Exclusion criteria: Patients < 18 years of age;Pregnancy

Design outcomes

Primary

Measure	Time frame
The main endpoint of this study is to describe the trend of the main microcirculatory parameters in the context of critical illness. The three determinants of microcirculation function that can be studied with hand-held vital microscopy are convection, diffusion and leukocyte function.Convection parameters describe red blood cells flow, and are the RBCv and/or MFI; Diffusive parameters describe the distance oxygen must travel from the RBC to the tissue cells and are the TVD, the PPV and the FCD, together with the tRBCp and the capillary hematocrit;Leukocytes are visualized as white spots in the context of black haemoglobin-containing vessels and can be numbered and identified as rolling (activated) or non-rolling on the vascular walls.	—

Measure

Time frame

The main endpoint of this study is to describe the trend of the main microcirculatory parameters in the context of critical illness. The three determinants of microcirculation function that can be studied with hand-held vital microscopy are convection, diffusion and leukocyte function.Convection parameters describe red blood cells flow, and are the RBCv and/or MFI; Diffusive parameters describe the distance oxygen must travel from the RBC to the tissue cells and are the TVD, the PPV and the FCD, together with the tRBCp and the capillary hematocrit;Leukocytes are visualized as white spots in the context of black haemoglobin-containing vessels and can be numbered and identified as rolling (activated) or non-rolling on the vascular walls.

—

Secondary

Measure	Time frame
non-applicable	—

Countries

Netherlands

Contacts

Public ContactW. Dam

Erasmus MC, Universitair Medisch Centrum Rotterdam

w.vandam@erasmusmc.nl0683344221

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)