Cancer, Carcinoma, malignancies
Conditions
Interventions
Patients in the intervention arm will be offered a combined lifestyle intervention guided by a lifestyle coach and oncology nurse. The intervention consists of an intensive intervention phase of 6 mon
Group sessions take place near the home of the patients. 
The control patients will receive four online group sessions with a lifestyle coach and all educational materials after the intervention period of 6 months.
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: To be eligible to participate in this study, a participant must:Be diagnosed with an invasive or haematological cancer type Be within five years post-primary treatment with curative intent OR having advanced cancer (stage IV) with a prolonged life expectancy (chronic cancer patients). Primary treatment in this context, includes among others surgery (> 3 months ago), radiotherapy, and/or chemotherapy or stem cell transplant in case of haematological cancers. Report a reduced HRQoL, i.e., a low score on at least 2 of the functioning scales and/or the symptom scale fatigue of the EORTC-QLQ-30 based on the thresholds of clinical importance of Giesinger et al. Be 40 years of age or older. Be able to speak and understand Dutch
Exclusion criteria
Exclusion criteria: A participant who meets any of the following criteria will be excluded from participation in this study:o Following, or planning to follow a combined lifestyle intervention (i.e., one of the existing interventions for overweight) during the intervention periodo Patients in the terminal phase (life expectancy < 3 months)o Mental or behavioural problems that hinder participating in group lifestyle coaching indicated by the health care professional who is referring to GLINK or by the study teamo Any circumstances that would impede the ability to give informed consent or adherence to study requirements as determined by the study team or treating physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is HRQoL measured with the EORTC QLQ-C30 summary score at 6 months after baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes:Function and symptom scales of Health-related Quality of Life (EORTC-QLQ-C30)Cancer-related fatiguePositive Health (Positive Health measurement model)Sleep hygiene (SHI)Physical Activity (SQUASH & ActivPAL)Diet components: fruit and vegetables, red and processed meat, alcohol, and nutritional supplementsSmoking status (yes/no) and packyearsAnthropometrics (height, weight, waist, body composition)Cost-effectiveness (EQ-5D-5L, societal and healthcare costs)Safety: (serious) adverse events | — |
Countries
Netherlands
Contacts
Public ContactEM Monninkhof
Universitair Medisch Centrum Utrecht
Outcome results
None listed