Comparing oxycodone and morphine in relation to long-term opioid use.

Comparing Oxycodone and Morphine as First-Choice Opioids in Postoperative Pain Management: Impact on Long-Term Use. - Oxycodone versus morphine - longterm postoperative opioid use

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON57504

Enrollment

1600

Registered

2025-03-27

Start date

2023-10-01

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General orthopedic surgery

Interventions

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The intervention to be examined in this study will involve the modification of the postoperative pain protocol. In the current protocol, oxycodone is the first-choice opioid, morphine the second choic

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria:  Patients who undergo orthopedic surgery and are admitted to the clinical orthopedic department of the Sint Maartenskliniek. 

Exclusion criteria

Exclusion criteria:  Patients who undergo orthopedic surgery within 3 months prior to or more than 3 months after the index date, or who refuse to be contacted via email or to participate in scientific research. 

Design outcomes

Primary

Measure	Time frame
The proportion of patients with new long-term opioid use. Long-term opioid use was defined as the use of any type of opioids, regardless of dose, six months after orthopaedic surgery.	—

Secondary

Measure	Time frame
On the day of hospital discharge:Daily opioid dose during hospital stay (OMEDD).Pain score on the day of hospital discharge (NRS).At 6 months postoperatively:The proportion of patients with new long-term opioid use (>6 months).Daily opioid dose (OMEDD).Opioid-related side effects.Pain scores (NRS).	—

Countries

Netherlands

Contacts

Public ContactEJ Melis

Sint Maartenskliniek

e.melis@maartenskliniek.nl024-3272789

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)