AERO-P/LOTUS

Asthma exacerbations - reduction of prednisolon use through optimized care/Exploring future high OCS use after asthma-related ER visit: the role of pre-exacerbation ICS and OCS use - OCS use after asthma-related ER visit

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57499

Enrollment

250

Registered

2025-02-03

Start date

2025-04-30

Completion date

Unknown

Last updated

2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients who meet the inclusion criterion below will be included in the study:Patients (18 years and older) who visited the emergency room of Frisius MC with an asthma exacerbation between May 1, 2022 and May 1, 2024. 

Exclusion criteria

Exclusion criteria: Patients who meet any of the exclusion criteria below will not be included in the study:The patient does not consent to participate in the study.The patient has an inflammatory comorbidity for which corticosteroids are used, to ensure that all OCS use is related to the treatment of asthma and thus avoid confounders.

Design outcomes

Primary

Measure	Time frame
Do patients with follow-up occurring <12 weeks after an asthma exacerbation requiring an SEH visit have less uncontrolled asthma in the year after SEH visit?Is (the change in) asthma medication use before and after an SEH visit due to an exacerbation related to OCS use in the following year? This is analysed for both the total patient group and divided into subgroups with high OCS use and no/low OCS use.	—

Measure

Time frame

Do patients with follow-up occurring <12 weeks after an asthma exacerbation requiring an SEH visit have less uncontrolled asthma in the year after SEH visit?Is (the change in) asthma medication use before and after an SEH visit due to an exacerbation related to OCS use in the following year? This is analysed for both the total patient group and divided into subgroups with high OCS use and no/low OCS use.

—

Secondary

Measure	Time frame
Descriptive medication use before and after ER visit	—

Countries

Netherlands

Contacts

Public ContactM Ploeg

Medisch Centrum Leeuwarden (MCL)

michelle.van.der.ploeg@frisiusmc.nl(058) 286 3185

Outcome results