BOOST - BMI of children with diabetes type 1: a study on the transition to smart technology

Effect of Advanced Hybrid Closed Loop (AHCL) pump therapy on the BMI of children with diabetes type 1 - BOOST - BMI of children with diabetes type 1: a study on the transition to smart technology

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57494

Enrollment

200

Registered

2025-03-25

Start date

2025-04-01

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes (mellitus) type 1

Interventions

Subcutaneous insuline injections (multiple dose injections, MDI) and advanced hybrid closed loop (AHCL) pump therapy.&nbsp

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Treatment with MDI (multiple dose injections, subcutaneous insulin injections) or AHCL  (advanced hybrid closed loop pump therapy) At least one year of treatment with either MDI or AHCL  Ages >3 and <18 years 

Exclusion criteria

Exclusion criteria: Hypo- of hyperthyroidism Celiac disease Diabetes type 2 MODY (pathogenic mutation) Eating disorder (e.g. anorexia nervosa of bulimia nervosa

Design outcomes

Primary

Measure	Time frame
Change in BMI SDS during treatment with AHCL, compared to change in BMI SDS during treatment with MDI. The outcome is based on age, weight and length, which is measured every four months at the outpatient clinic.	—

Secondary

Measure	Time frame
Cardiovascular risk factors: (systolic) blood pressure, cholesterol, triglycerides, liver enzymes.  Blood glucose regulation: HbA1c, Time-In-Range.	—

Countries

Netherlands

Contacts

Public ContactJS Renes

Albert Schweitzer Ziekenhuis

diatime@asz.nl078-6545139

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)