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The effect of milk consumption on the blood microbiome (MAMI study) in healthy volunteers

The effect of milk consumption on the blood microbiome (MAMI study) in healthy volunteers - MAMI study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON57456
Enrollment
10
Registered
2025-05-06
Start date
2025-07-08
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

microbiome microbiota microflora

Interventions

The participants will abstain from consumption of any dairy product for ten days, and subsequently drink milk for consecutive 7 days (700 millimetre per day), while concomitant consumption of other

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Age 18-65 years - 18.5 =

Exclusion criteria

Exclusion criteria: - Regular use medications such as antibiotics, steroids, beta blockers, and adrenergic-stimulating agents (self-report) - Regular use prebiotic and/or probiotics apart from yoghurt and young soft cheese (self-report) - Antibiotic intake in the previous months (self-report) - Daily consumption of more than 10 cigarettes (self-report) - Chronic diseases including type 2 diabetes, hypertension, fatty liver disease, cancer, or autoimmune disease (self-report) - Internal diseases, including those of the gastrointestinal tract, lung, heart, vasculature, liver, and kidney (self-report) - Eating disorder or unconventional eating habits (self-report) - Participation in another study (self-report) - Women: pregnancy and breastfeeding (self-report)

Design outcomes

Primary

MeasureTime frame
Lactococcus DNA counts before, during and end of the milk-consumption intervention.

Secondary

MeasureTime frame
Other microbiome DNA counts (bacteria, viruses and Archaea) in gut and blood before and after milk consumption.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)