Daylight during Recovery of Depression

Daylight during Recovery of Depression - DaR (Daylight and Recovery)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57455

Enrollment

Registered

2024-10-27

Start date

2026-04-23

Completion date

Unknown

Last updated

2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

clinical depression in remission Major Depressive Disorder (MDD) in remission Remission after depression

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) A past year diagnosis of a unipolar major depressive disorder according to DSM-5 criteria, 2) Full or partial remission, i.e. not meeting the DSM-5 criteria for a depressive episode within the past two months, 3) Age 20 years or older.

Exclusion criteria

Exclusion criteria: 1) Eye conditions affecting light transmittance to the retina, 2) An established or suspected diagnosis of a major neurocognitive disorder, 3) A severe mental illness, defined as a bipolar or primary psychotic disorder or a severe substance-use disorder in need of treatment, 4) Seasonal affective disorder, 5) Not able to fill out self-report questionnaires, 6) Shift work. 7) Regular usage of melatonin, within 3 weeks prior to the start of the measuring period. 8) Receiving light treatment

Design outcomes

Primary

Measure	Time frame
The main outcomes are positive and negative affect, operationalized as momentary positive (PA) and negative affect (NA) based on the circumplex model of affect. The main determinant is time spent in (day)light, assessed with a question in the diary in three time intervals per day (morning, afternoon, and evening), and assessed objectively with the light sensor as time spent in >1000 lux. We will assess which operationalization is the strongest predictor of affect.	—

Measure

Time frame

The main outcomes are positive and negative affect, operationalized as momentary positive (PA) and negative affect (NA) based on the circumplex model of affect. The main determinant is time spent in (day)light, assessed with a question in the diary in three time intervals per day (morning, afternoon, and evening), and assessed objectively with the light sensor as time spent in >1000 lux. We will assess which operationalization is the strongest predictor of affect.

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Secondary

Measure	Time frame
General covariables used for every research question are physical activity, social interactions, exposure to green environments, use of medication and important events, which will be asked in the diary. Age, sex and education level, chronotype, depressive symptom severity and presence of sleep disturbances will be assessed during the baseline interview with questionnaires. The phase of the circadian pacemaker will be evaluated with dim light melatonin onset assessment at the end of the 30-day study period. Sleep will be assessed with actigraphy. For circadian rhythms, we will assess the interdaily stability, intradaily variability, and relative amplitude.	—

Measure

Time frame

General covariables used for every research question are physical activity, social interactions, exposure to green environments, use of medication and important events, which will be asked in the diary. Age, sex and education level, chronotype, depressive symptom severity and presence of sleep disturbances will be assessed during the baseline interview with questionnaires. The phase of the circadian pacemaker will be evaluated with dim light melatonin onset assessment at the end of the 30-day study period. Sleep will be assessed with actigraphy. For circadian rhythms, we will assess the interdaily stability, intradaily variability, and relative amplitude.

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Countries

Netherlands

Contacts

Public ContactM Zuidersma

Universitair Medisch Centrum Groningen

m.zuidersma@umcg.nl06-86558458

Outcome results