gezondheid en ziekten t.b.v. de volksgezondheid health and disease
Conditions
Interventions
None listed
Sponsors
RIVM
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Belonging to the subset of 5000 genotyped Doetinchem Cohort Study participants. - Already participated in the ongoing measurement round 8 of the Doetinchem Cohort Study.
Exclusion criteria
Exclusion criteria: - Cancer patients (past or present); - Individuals knowingly having an HIV or Hepatitis C infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Ability to generate hiPSCs and differentiated derivative cells from healthy somatic cells - Ability to generate mutated cell lines using gene-editing - Ability to study disease phenotype in mutated cell lines and compare it to the control iso-genic cell lines | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed