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hiPSC from Doetinchem Cohort Study round 8 2024-2028

hiPSC from Doetinchem Cohort Study round 8 2024-2028 - hiPSC from Doetinchem Cohort Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON57454
Enrollment
10
Registered
2025-04-28
Start date
2025-09-10
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gezondheid en ziekten t.b.v. de volksgezondheid health and disease

Interventions

None listed

Sponsors

RIVM
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Belonging to the subset of 5000 genotyped Doetinchem Cohort Study participants. - Already participated in the ongoing measurement round 8 of the Doetinchem Cohort Study.

Exclusion criteria

Exclusion criteria: - Cancer patients (past or present); - Individuals knowingly having an HIV or Hepatitis C infection.

Design outcomes

Primary

MeasureTime frame
- Ability to generate hiPSCs and differentiated derivative cells from healthy somatic cells - Ability to generate mutated cell lines using gene-editing - Ability to study disease phenotype in mutated cell lines and compare it to the control iso-genic cell lines

Secondary

MeasureTime frame
n.a.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)