cancer
Conditions
Interventions
Participants will undergo an MRI scan with a maximum duration of 90 minutes per
scan session. A maximum of 5 MRI scans per patient or volunteer can be
performed. Participants will be asked whether t
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - >= 18 years - Capable and prepared to sign informed consent - Healthy volunteers or cancer patients
Exclusion criteria
Exclusion criteria: - Contraindication for MRI scanning as listed in screening form - Neurological or psychiatric diagnosis making it impossible to remain fixed in the same position during the whole examination. - Refusal of subjects to be informed of chance findings possibly relevant to their health - In the case that study participation would interfere with regular treatment - Renal function is unknown - Renal function is below 30 ml/min - Refusal of subjects for the use of an oxygen mask throughout the scanning process - Contra-indication for receiving hyperoxic gas (moderate-severe COPD, GOLD stage 2-4).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optimization of the OE-MRI protocol and processing techniques required for OE-MRI imaging on the MR Linac system based on signal to noise ratio, contrast to noise and acquisition time. The study is successful when we arrive at parameter settings resulting in geometrically accurate scans that have the right contrast for the radiation oncologist to identify hypoxic regions. | — |
Countries
Netherlands
Outcome results
None listed