Surface Electrical Myography, Oxygen Consumption (VO2), Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit (ICU)

Surface Electrical Myography, Oxygen Consumption (VO2), Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit (ICU) - eSERA

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57451

Enrollment

Registered

2025-05-06

Start date

2025-06-01

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iedereen > 48 uur beademd voor welke reden dan ook Mechanical Ventilation Weaning from mechanical ventilation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Mechanically ventilated for 48 hours or more - 18 years of age or older - Esophageal catheter in situ (standard of care) - Eligible for an SBT in the near future according to the LUMC SBT protocol currently valid - Informed consent from the patient obtained before admission to the ICU, e.g. in case of planned surgery, or obtained from te patient on the ICU if the patient is able to give consent and has not given consent previously.

Exclusion criteria

Exclusion criteria: - Severe cardiac failure NYHA class IV without mechanical support (LVAD or Impella) - COPD Gold IV - Pregnancy - ECMO

Design outcomes

Primary

Measure	Time frame
Magnitude of the electric signal (base level, or tonic level, maximum level, AUC of the electric signal during contraction in inspiration and expiration, differences between maximum and tonic levels), VO2, PTP, WOB, RSBI, diaphragmatic pressure swing.	—

Secondary

Measure	Time frame
Secondary endpoints are the associations between the sEMG signals and the PTP, WOB, Esophageal pressure swings, VO2.	—

Countries

Netherlands

Outcome results