Chronic mesenteric ischemia Intra-arterial pressure measurements Mesenteric artery stenting Narrowed arteries of the digestive system
Conditions
Interventions
Dräger Infinity C300 external pressure measurement system (CE marked, MDD93/42, CE mark article code: OP90127). 
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. All patients with CMI undergoing an endovascular procedure of the mesenteric arteries2. Age =18 years of age 3. Patients who gave informed consent
Exclusion criteria
Exclusion criteria: 1. Patients presenting with acute mesenteric ischemia2. Common origin of the SMA and CA (normal variant)3. Contraindication of nitroglycerin4. Patients unable to give informed consent5. Pregnancy6. Other criteria the physician considers not compatible with this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the predictive performance of the Pd/Pa ratio before and after administration of a vasodilator to predict the clinical success ofmesenteric artery stenting. | — |
Secondary
| Measure | Time frame |
|---|---|
| - To assess the improvement in quality of life after a successful endovascular mesenteric artery revascularization procedure- To compare the improvement in quality of life between patients with pressure measurements indicating clinical success of revascularization and patients with pressure measurements indicating no clinical success of revascularization- To assess the cost-effectiveness of future implementation of intra-arterial pressure measurements prior to a mesenteric artery revascularization- To assess the predictive performance of pressure measurements to predict clinical success of mesenteric artery stenting in patients with stenosis of a single mesenteric artery.- To assess the predictive performance of pressure measurements to predict clinical success of mesenteric artery stenting in patients with stenosis of =2 mesenteric arteries.- To assess the predictive performance of pressure measurements to predict clinical success of mesenteric artery stenting in patients with a stenosis of 50-70%.- To assess the predictive performance of pressure measurements to predict clinical success of mesenteric artery stenting in patients with an in stent stenosis.- To determine the correlation of pressure measurements with the severity of stenosis.- To determine the duration of pressure measurements.- Register complications within 30 days after mesenteric artery pressure measurements.- To compute the pressure drop using computational models- To compare the computed to the measured pressure drop | — |
Countries
Netherlands
Contacts
Public ContactK. Pieterman
Erasmus MC, Universitair Medisch Centrum Rotterdam
Outcome results
None listed