neurodegenerative disorders dysarthria Pathological speech
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Native speaker of Dutch Only for the group of people with a sensorimotor disorder: - Diagnosed with Parkinson's disease Only for the group of people with a cognitive disorder: - Diagnosed with mild cognitive impairment Only for the group of control participants: - No prior speech or language impairments
Exclusion criteria
Exclusion criteria: - Lack of ability to give informed consent (i.e., incapacitation) - in any case of doubt, the (in-)capacitation will be determined by a physician - History of stroke or other neurological or psychological disorder - Self-reported signs of depression - Stuttering or other speech and language problems that are not related to PD or MCI - Severe impairment of vision - Metal at or close to the head, chest or abdomen (e.g., piercings, pacemaker, etc.) - History of Deep Brain Stimulation (DBS)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The most important research parameters are acoustic changes of speech in response to feedback perturbations and kinematic measures of breathing. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary study endpoints are acoustic measurements of voice pitch, acoustic characteristics of articulation during unperturbed speech and subjective speech complaints. | — |
Countries
Netherlands