Joining forces to assess (determinants of) lifestyle behavior, morbidity and mortality among multimorbid individuals with a combination of the chronic diseases type 2 diabetes mellitus, cardiovascular disease, chronic respiratory diseases and/or cancer: the LifeStyle Medicine for individuals with multiple chronic diseases (LifeMeds) cohort.

Joining forces to assess (determinants of) lifestyle behavior, morbidity and mortality among multimorbid individuals with a combination of the chronic diseases type 2 diabetes mellitus, cardiovascular disease, chronic respiratory diseases and/or cancer: the LifeStyle Medicine for individuals with multiple chronic diseases (LifeMeds) cohort. - LifeMeds

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57412

Enrollment

3000

Registered

2025-03-31

Start date

2025-03-01

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

multimorbiditeit (type 2 diabetes, hart- en vaatziekten, chronische luchtwegaandoeningen en/of kanker) comorbidity multimorbidity multiple chronic diseases

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - The cohort will include participants who have been diagnosed with at least two of the following chronic diseases: T2DM, CVD, CRD, cancer. The study will specifically include most common subtypes of diseases with etiologies strongly linked to lifestyle-related risk factors: 1. Cancer: breast, colorectal, prostate, lung/ brochus. 2. T2DM 3. CVD: coronary artery heart disease, heart failure, peripheral artery disease, hypertension. 4. CRD: chronic obstructive pulmonary disease, asthma. - Aged 18 years or older

Exclusion criteria

Exclusion criteria: - Refusal to informed consent - Have significant cognitive impairment (e.g. major neurocognitive disorder)

Design outcomes

Primary

Measure	Time frame
Lifestyle variables include physical activity, dietary intake, alcohol consumption, sleep, stress, medication adherence, smoking and weight control. Determinants include sociodemographic, medical, social and psychological factors. Endpoints: - Mortality: all-cause and cardiovascular - Hospitalizations during the first year post- percutaneous coronary intervention, includ-ing elective and acute hospitalizations. - Major Adverse Cardiac Events (myocardial infarction, coronary artery bypass graft, heart transplantation, revascularization)	—

Measure

Time frame

Lifestyle variables include physical activity, dietary intake, alcohol consumption, sleep, stress, medication adherence, smoking and weight control. Determinants include sociodemographic, medical, social and psychological factors. Endpoints: - Mortality: all-cause and cardiovascular - Hospitalizations during the first year post- percutaneous coronary intervention, includ-ing elective and acute hospitalizations. - Major Adverse Cardiac Events (myocardial infarction, coronary artery bypass graft, heart transplantation, revascularization)

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Countries

Netherlands

Outcome results