amblyopia (lazy eye) Glaucoma
Conditions
Interventions
None listed
Sponsors
Netherlands Institute for Neuroscience
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Male or female 18 years or older Healthy, English or Dutch speaking Patients with glaucoma, amblyopia, also healthy controls (no visual disorder)
Exclusion criteria
Exclusion criteria: Personal history of psychiatric or neurological disorder. This includes dementia; alzheimers; multiple sclerosis; parkinsons and epilepsy. Psychiatric disorders excluded include schizophrenia; and autism. Contraindications for MRI: including claustrophobia and tinnitus. Participants cannot have any medical implants: pacemakers, surgical aneurysm clips, and other known metal fragments embedded in the body, including eyes. Cannot have had surgery in the past 6 weeks. Significant previous adverse response to fMRI scanning. Participant does not speak English or Dutch
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in overall sensitivity (area under the curve, from the nCSF model) between patients and controls | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of overall sensitivity between the eyes of patients (i.e., left vs right) Relation of model parameters (i.e., overall sensitivity; pRF size) with basic visual functions (visual acuity; perceptual contrast sensitivity) | — |
Countries
Netherlands
Contacts
Public ContactSD Dumoulin
Netherlands Institute for Neuroscience
Outcome results
None listed