central sensitization
Conditions
Interventions
Niet van Toepassing
Sponsors
Research Group Biomedical Signal and Systems (BSS), University of Twente
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 40 years old
Exclusion criteria
Exclusion criteria: - Participant refusal during the study - Language problems - Skin problems at site of stimulation or EEG recording - Diabetes - Small fiber neuropathy - Implanted stimulation device - Pregnancy - Usage of analgesics within 24 hours before the experiment - Consumption of alcohol or drugs within 24 hours before the experiment - Pain complaints at the time of the experiment - A medical history of chronic pain - Having a position of dependency on one or more of the researchers (i.e. being directly supervised and graded by one of the researchers).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NDTs, EPs, and subjective ratings (NRS) of the perceived strength of mechanical punctuate stimuli will be collected from a testing (HFS) and a control site, before and 20 minutes after induction of secondary hyperalgesia using HFS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Response Time: Subject*s response time. Participant Characteristics: Age and sex, handedness. | — |
Countries
Netherlands
Contacts
Public ContactJ.R. Buitenweg
Universiteit Twente
Outcome results
None listed