afib Atrial fibrillation
Conditions
Interventions
None listed
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Participant AFACT-trial, comprising of patients who had advanced AF and were randomized to thoracoscopic pulmonary vein isolation for AF with or without aditional epicardial ganglion plexus ablation.
Exclusion criteria
Exclusion criteria: Refusal to be contacted for future studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameter/endpoint: The primary endpoint of the study is freedom of AF after ten years after the procedure without the use of antiarrhythmic drugs. Freedom of AF is defined as the absence of documentation of episodes of AF, atrial flutter or atrial tachycardia >30 seconds on all holters and ECG recordings during follow up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters/endpoints: - Classification of AF recurrence (paroxysmal, persistent, permanent AF, and atrial tachycardia). - Left Atrial (LA) Volume and Function 8 to 10 years post procedure - Difference in Quality of Life from baseline to ten years post-procedure in points - Number and reasons for pacemaker implants during the ten-year follow-up period. - Number and reasons for additional ablation procedures during the ten-year follow-up period. - Occurrence of major adverse events (heart failure, stroke, major bleeding, mortality) during the follow-up period. - Causes of death during the ten year follow-up. - Freedom of AF with AADs, defined as the absence of documentation of episodes of AF, atrial flutter or atrial tachycardia >30 seconds since start of the last dose of AAD, measured at the time of data collection 10 years safter the procedure. | — |
Countries
Netherlands
Outcome results
None listed