Long-term follow-up of the offspring born to mothers with a solid organ transplant.

Long-term follow-up of the offspring born to mothers with a solid organ transplant. - Transplantlines Next Generation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57189

Enrollment

210

Registered

2023-12-06

Start date

2025-10-15

Completion date

Unknown

Last updated

2025-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular disease, nephrological disease

Interventions

Product is the evaluation of the overall health of the offspring of mothers with a SOT.

Eligibility

Age

No minimum to 64 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all  of the following criteria: • Mother with a Kidney Tx, Liver Tx, Pancreas Tx, Pancreas islet Tx, Heart Tx or Lung Tx before pregnancy  (including mothers with multiple transplantation types) • Age >=16 years for offspring born to mother with a KTx or LiTx

Exclusion criteria

Exclusion criteria: • No informed consent • Non Dutch or English speaking

Design outcomes

Primary

Measure	Time frame
The primary endpoints of the study focus on cardiovascular health and the presence of kidney disease in participants >16 years, and overall health in participants =	—

Secondary

Measure	Time frame
Secondary aims are the immunological status, including microbiome and the overall development of the offspring. Third, we want to assess if there are differences between the health of the offspring born to mothers with a KTx, LiTx, PTx, HTx and LuTx.	—

Countries

Netherlands

Contacts

Public ContactMFC Jong

Rijksuniversiteit Groningen

m.f.c.de.jong@umcg.nl0503616161

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)