acne ectopica Hidradenitis Suppurativa
Conditions
Interventions
None listed
Sponsors
The European Hidradenitis Supurativa Foundation (EHSF) e.V.
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Male or female, age 18 years or older at the screening visit • Patients must have a diagnosis of HS (in compliance with Dessau criteria as modified in San Francisco) for at least one year (365 days) prior the screening visit • HS lesions must be present in at least two distinct classical anatomic areas (e.g., left and right axilla; or left axilla and left inguino-crural fold) • Willing and able to comply with clinic visits and study-related procedures • Provide informed consent signed by study patient or legally acceptable representative • Able to understand and complete study-related material
Exclusion criteria
Exclusion criteria: - Presence of skin comorbidities (e.g. inverse psoriasis, epidermal inclusion cyst) that may interfere with study assessments for HS - Severe concomitant illness(es) - Pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whole-exome sequencing and/or array genotyping to identify single variants and/or gene-based burden tests significantly associated with HS status and severity. | — |
Secondary
| Measure | Time frame |
|---|---|
| Transcriptional profiling through bulk RNA sequencing. | — |
Countries
Netherlands
Outcome results
None listed