Protein metabolism protein turnover
Conditions
Interventions
Participants will consume 40 grams of intrinsically L-[1-13C]-phenylalanine
labelled milk protein, dissolved in 400 mL water on the evening before planned
surgery.
Sponsors
Universiteit Maastricht
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: Adults 1. >= 18 years old 2. Planned surgery that involves the (partial) resection of organ tissue 3. 18.5 = 8 years old and
Exclusion criteria
Exclusion criteria: 1. Lactose intolerant or allergy to milk proteins 2. Recent (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the incorporation of dietary protein-derived amino acids in different organ tissues, expressed as % of ingested amount of protein. | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect that in most surgical procedures, muscle tissue will be removed as part of the standard surgical procedure. The second study parameter is the incorporation of dietary protein-derived amino acids in muscle tissue, expressed as % of ingested protein. In case no muscle tissue will be removed as part of the standard surgical procedure, this outcome will not be calculated for that specific participant. | — |
Countries
Netherlands
Contacts
Public ContactL.J.C. Van Loon
Universiteit Maastricht
Outcome results
None listed