Effect of oat-coated disposable gloves compared to non-coated disposable gloves, in health care workers, with high glove consumption, on skin condition and user experience.

Effect of oat-coated disposable gloves compared to non-coated disposable gloves, in health care workers, with high glove consumption, on skin condition and user experience. - COAT

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON57130

Enrollment

600

Registered

2024-08-12

Start date

2024-11-18

Completion date

Unknown

Last updated

2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hand dermatitis hand eczema hand eczema

Interventions

HCW in the intervention arm will receive disposable nitrile examination gloves with an oat coating and HCW in the care as usual arm will receive non coated disposable nitrile gloves, as HCW currentl

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: healthcare workers with prolonged wearing of occlusive disposable gloves

Exclusion criteria

Exclusion criteria: not using disposable gloves during workKnown to have an oat allergy

Design outcomes

Primary

Measure	Time frame
The main study parameters are the prospective analysis of skin condition of the hands of the HCW and their user experience. The primary endpoint is the difference in change in Hand Eczema Severity index (HECSI), from baseline to 6 months between HCW using the oat coated gloves (intervention group ) and HCW using non-coated gloves ( care as usual group.	—

Secondary

Measure	Time frame
Secondary endpoints are the difference in patients reported outcomes (Quality of Life in Hand Eczema Questionnaire (QLHEQ), user experience questionnaire- short version (UEQ-S)) between groups. Furthermore differences in Trans Epidermal Water Loss (TEWL), skin hydration, skin erythema and levels of inflammatory cytokines and natural moisturizing factors (NMF) in tape strips are measured between the intervention and control group. Additionally, implementation outcomes will be assessed using semi-structured interviews.	—

Measure

Time frame

Secondary endpoints are the difference in patients reported outcomes (Quality of Life in Hand Eczema Questionnaire (QLHEQ), user experience questionnaire- short version (UEQ-S)) between groups. Furthermore differences in Trans Epidermal Water Loss (TEWL), skin hydration, skin erythema and levels of inflammatory cytokines and natural moisturizing factors (NMF) in tape strips are measured between the intervention and control group. Additionally, implementation outcomes will be assessed using semi-structured interviews. 

—

Countries

Netherlands

Contacts

Public ContactL.E. Langlah

Amsterdam UMC

COAT@amsterdamumc.nl020-5667792

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 23, 2026