OA Pearl 1

Towards the primary prevention of hip OA - pilot study - OA Pearl 1

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57090

Enrollment

150

Registered

2024-06-18

Start date

2025-02-11

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis of hip

Interventions

Not applicable.

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Aged 18-55 years - Self-reported participation in high loading sports when aged 10 through 16 for >=2 days/week for >=1 year - Willing to visit the research center for physical examination and radiography - Master the Dutch language

Exclusion criteria

Exclusion criteria: - Pregnancy - If both hips meet any of the following criteria: * Medical diagnosis of hip OA (diagnosed by their GP or healthcare specialist) * Meeting the NICE criteria for hip OA * Previous hip surgery

Design outcomes

Primary

Measure	Time frame
The primary outcome for the current pilot will be the feasibility of the proposed recruitment strategies. We deem the pilot to be feasible when out of a maximum of 150 participants, 30 (20%) participants are eligible after the physical examination and radiography to participate in the proposed preventive trial.	—

Secondary

Measure	Time frame
The secondary study parameters/endpoints (the feasibility for the willingness of potential participants) will be met if >=75% of the eligible participants (i.e., with cam morphology and no hip OA on radiography) is willing to participate in the future prevention trial. Other study parameters: Hip MR images, obtained in 30 participants only, will be assessed using the semi-quantitative SHOMRI scoring system. Furthermore, for each recruitment strategy, we will determine: 1. The efforts; the costs for personnel and material. 2. The outcome; the number of individuals contacting the research center. 3. The effectiveness of registration; the percentage of individuals fulfilling the telephonic selection criteria. 4. The effectiveness of screening; the percentage of individuals with cam and no radiographic hip OA.	—

Measure

Time frame

The secondary study parameters/endpoints (the feasibility for the willingness of potential participants) will be met if >=75% of the eligible participants (i.e., with cam morphology and no hip OA on radiography) is willing to participate in the future prevention trial. Other study parameters: Hip MR images, obtained in 30 participants only, will be assessed using the semi-quantitative SHOMRI scoring system. Furthermore, for each recruitment strategy, we will determine: 1. The efforts; the costs for personnel and material. 2. The outcome; the number of individuals contacting the research center. 3. The effectiveness of registration; the percentage of individuals fulfilling the telephonic selection criteria. 4. The effectiveness of screening; the percentage of individuals with cam and no radiographic hip OA.

—

Countries

Netherlands

Contacts

Public ContactM Vlastuin

Erasmus MC, Universitair Medisch Centrum Rotterdam

kwaliteitHAG@erasmusmc.nl0107041393

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)