Gezonde deelnemers, dus geen aandoeningen Not applicable
Conditions
Interventions
Two study products will be investigated, both commercially available dairy
products being a fermented milk product and a non-fermented milk product:
Product A: Yoghurt
Product B: Full fat pasteuri
Sponsors
Nutricia Research
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 and = 18.5 and
Exclusion criteria
Exclusion criteria: 1. Any known surgery or ongoing medical condition that interferes significantly with protein absorption and digestion, and/or gastrointestinal (GI) function (e.g. phenylketonuria, pancreatitis, short bowel syndrome, inflammatory bowel disease, gastroesophageal reflux disease, celiac disease, gastric ulcer, chronic gastritis, gastrointestinal cancer, oesophageal and/or gastric surgery), in opinion of the investigator.* 2. Known renal or hepatic diseases that may interfere with protein metabolism, including but not limited to acute hepatitis, chronic liver disease, nephritis, cystinuria, chronic kidney disease, in the opinion of the investigator. 3. Use of systemic medication within the past 3 weeks prior to screening which in the opinion of the investigator may influence gastric acid production and/or gastrointestinal motility or function and/or protein metabolism (for example: antibiotics, anticonvulsants, prokinetics, antacids or gastric acid inhibitors, opioid analgesics, anticoagulants, corticosteroids, laxatives, growth hormone, testosterone, immunosuppressants, or insulin). 4. Known Diabetes Mellitus type I or type II, insulin resistance or metabolic syndrome. 5. Any ongoing cancer and/or cancer treatment*(except for non-melanoma skin cancer or carcinoma in situ).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare product A vs product B by means of total postprandial blood amino acid concentrations expressed as incremental Area Under the Curve iAUC. | — |
Secondary
| Measure | Time frame |
|---|---|
| o compare product A vs product B by means of essential postprandial blood amino acid (EAA) concentrations expressed as incremental Area Under the Curve iAUC. To compare product A vs product B by means of maximum incremental concentration (iCmax) of total postprandial blood amino acids (TAA) and as time until maximum concentration (Tmax). To compare product A vs product B by means of maximum incremental concentration (iCmax) of essental postprandial blood amino acids (EAA) and as time until maximum concentration (Tmax). | — |
Countries
Netherlands
Outcome results
None listed