Understanding clot structure in thrombosis and bleeding disorders

Understanding clot structure in thrombosis and bleeding disorders - Understanding clot structure in thrombosis and bleeding disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57046

Enrollment

Registered

2024-10-04

Start date

2024-09-01

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bleeding disorder cardiovascular disease thrombosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Voluntarily particiation, Between 18-70 of age, Written informed consent

Exclusion criteria

Exclusion criteria: Known disease that affects coagulation; Treatment with medication that interferes with coagulation

Design outcomes

Primary

Measure	Time frame
In this fundamental research project, we study determinants of the clot structure and how they affect the clot architecture and physical properties. For example, the stiffness of the clot, fiber diameters, rate of fibrinolysis and interaction of coagulation factors with cells or the endothelium will be studied in varying conditions (e.g. modified fibrinogen, presence or absence of flow).	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results