migraine headache disorder
Conditions
Interventions
Not applicable.
Sponsors
Hersenstichting
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - =18 years of age - Fulfil ICHD-3 criteria for episodic migraine - Must experience active migraine; which is defined for this study as at least 1 attack per month, but preferably at least 2
Exclusion criteria
Exclusion criteria: - Unable or unwilling to use the headache E-dairy on a daily basis; - Diagnosed with other (chronic) neurological diseases such as Parkinson’s disease, epilepsy etc. that may interfere with the results of this study; - Chronic migraine as defined by the ICHD-3; - Severe depression and/or panic disorders and/or schizophrenia and/or psychiatric disorders; - Inability to differentiate between migraine and other headaches; - Comorbidity with Cluster Headache or other TACs.Insufficient proficiency in the Dutch language to complete the headache e-diary.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to identify cortical excitability features, in the form of VEP-EEG changes, in the pre-ictal phase of a migraine attack that can serve as a marker for decreased threshold and upcoming migraine attacks. | — |
Secondary
| Measure | Time frame |
|---|---|
| - To assess and optimize EEG data quality and user-friendliness of data acquisition in the home environment compared to when performed in clinic. - To assess feasibility of integrating E-headache diary information and EEG changes in the pre-ictal phase into developing a personalized prediction model for upcoming migraine attacksTo record VEP-EEG during an aura attack. | — |
Countries
Netherlands
Contacts
Public ContactG.M. Terwindt
Leids Universitair Medisch Centrum
Outcome results
None listed