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Studying extracellular vesicles in immune thrombocytopenia

Studying extracellular vesicles in immune thrombocytopenia - Extracellulair vesicles in ITP

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON57039
Enrollment
10
Registered
2024-10-08
Start date
2024-10-15
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Immune thrombocytopenia

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult patients with ITP Informed consent will be obtained

Exclusion criteria

Exclusion criteria: Patients with secondary ITP Patients with antiplatelet therapy

Design outcomes

Primary

MeasureTime frame
Concentration of EVs in ITP patients; Wilcoxon signed rank tests will be used to compare EV concentrations between groups. Of interest are EVs derived from platelets (CD61+), activated platelets (CD62p+) and erytrocytes (CD235a+).

Secondary

MeasureTime frame
Association of (platelet-derived) EVs with age, sex and current/past therapy.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)