Obsessive-Compulsive Disorder OCD Compulsive thoughts and behaviors
Conditions
Interventions
N.A.
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for HC: - The subject provides written informed consent attesting to their understanding of the study's objectives and the procedures involved, as well as their willingness to participate. - The volunteer is healthy, i.e. absence of all exclusion criteria - Age between 18-65 years old Inclusion criteria for OCD patients: - Clinical diagnosis of OCD - The subject provides written informed consent attesting to their understanding of the study's objectives and the procedures involved, as well as their willingness to participate. - Absence of all exclusion criteria for OCD patients - Age between 18-65 years old
Exclusion criteria
Exclusion criteria: Exclusion criteria for HC: - Current psychiatric/neurological diagnosis - History of psychiatric treatment - Current use of psychoactive medication - Standard contra-indications for magnetic resonance imaging - Current substance abuse (e.g. (excessive) use of drugs or alcohol) Exclusion criteria for OCD patients: - Current substance abuse (e.g. excessive use of drugs or alcohol) - Standard contra-indications for magnetic resonance imaging
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes for this study are the functional connectivity profiles of the STN and the VS from each group during the cognitive and affective tasks, measured with BOLD-fMRI. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes for this study are the answers on the Y-BOCS, MADRS, STAI and POMS questionnaires. Other secondary outcomes are the performance on the (computer) tasks (Trail Making and Emotional-Stroop) and MRI tasks, described by the reaction time and accuracy rating scores. | — |
Countries
Netherlands
Contacts
Public ContactT Branco Nunes
Universiteit Maastricht
Outcome results
None listed