no condition, healthy volunteers not applicable
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: • 18 - 50 years old. • Normal hearing as assessed with the hearing threshold measurement in Session 1 (that is, hearing thresholds > -20 dB).
Exclusion criteria
Exclusion criteria: • A history of neurological and/or psychiatric disorders. • Participants that do not meet the MRI safety criteria will be excluded from the study: - Epilepsy. - Heart rhythm disorder. - Diabetic. - Large and/or ferromagnetic parts in the head (except for a dental wire). - Active implant (e.g. pacemaker, neurostimulator, insulin pump, ossicle prosthesis, or residual leads). o Claustrophobia. o Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • Functional brain scans: Recording neural responses to naturalistic, spatial sounds while participants perform a simple one-back memory task to ensure attentive listening. • Behavioural sound localisation task: Accuracy. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Recording of spatial cues: Measurements of the head-related impulse response (HRIR12,13). • Structural brain scans: Map of brain anatomy in order to associate neural responses to sound as measured with the functional brain scans to anatomical locations in the brain. • Hearing test: Hearing thresholds for pure tones. | — |
Countries
Netherlands