Stoornis in het gebruik van cocaïne cocaine addiction Cocaine use disorder
Conditions
Interventions
None listed
Sponsors
Indigo i-psy PsyQ Brijder B.V.
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: 1. Age between 18 and 65 years of age; 2. Moderate or severe cocaine use disorder according to DSM-5 (>=4 criteria); 3. Active participation in heroine-assisted treatment; 4. Snorting, inhaling or injecting cocaine use as primary route of administration; 5. Able and willing to provide one blood sample; 6. Able and willing to provide urine- and saliva-samples and to be interviewed about recent drug use for 2 times per week during 4 consecutive weeks; 7. Understanding and speaking Dutch; 8. Able and willing to give written informed consent.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: 1. Does not have a sufficiently good understanding of Dutch for informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To observe the metabolic profile of cocaine in urine, saliva and blood of volunteers with cocaine use disorder participating in heroin-assisted treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| To explore whether the bioanalytical method for determining cocaine use in patients with cocaine use disorder could be improved by quantitative measurement, measurement of a metabolite other than benzoylecgonine, or measurement in a different biomatrix (saliva). | — |
Countries
Netherlands
Outcome results
None listed