Comparing dynamic contrast enhanced CT with Rb-82 PET for myocardial perfusion assessment in patients with suspicion for chronic coronary syndrome: The DYNAMORE study

Comparing dynamic contrast enhanced CT with Rb-82 PET for myocardial perfusion assessment in patients with suspicion for chronic coronary syndrome: The DYNAMORE study - DYNAMORE study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56989

Enrollment

Registered

2024-08-23

Start date

2024-10-07

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic coronary syndrome ischemic heart disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients who underwent clinically indicated MPI Rb-82 PET - Age >= 55 - Written informed consent

Exclusion criteria

Exclusion criteria: - Patients who underwent a coronary CTA

Design outcomes

Primary

Measure	Time frame
The myocardial flow reserve measured with DCE-CT in comparison to myocardial flow reserve measured with Rb-82 PET. The myocardial flow reserve (MFR) is calculated as the ratio of stress to rest myocardial blood flow.	—

Secondary

Measure	Time frame
Secondary Objective(s): 1. To compare DCE-CT and Rb-82 PET myocardial blood flow on rest and stress acquisitions separately, as well as on a segment and vessel territory level 2. To assess the clinical utility of DCE-CT for myocardial perfusion assessment in comparison to Rb-82 PET.	—

Countries

Netherlands

Outcome results