Anemia
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: • Age over 18 years, of any gender and ethnic background • Admitted to the intensive care unit • Able to give informed consent • Patients with an arterial line as part of their treatment plan. • Patients able to remain seated in chair for at least 30 minutes • Patients able to remain supine overnight for at least 6 hours
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: • Delirium or inability to give informed consent • Inability to understand written information in Dutch • Patients on artificial ventilation • Orotracheally intubated patients (spontaneous breathing through a tracheostomy cannula is allowed) • Patients treated with noradrenaline > 0.05 ug/kg/min • Patients treated with argipressin • Patients who received a blood transfusion within 24 hours before measurements • Patients who received > 3 L of intravenous fluids within 24 hours before measurements • Patients who received > 500 ml of iv fluids within 4 hours of measurements • Severe restlessness or inability to remain supine for 6 hours before initial blood sampling • Patients being treated with diuretics • Patients admitted with: • Decompensated right heart failure • Pulmonary hypertension • Pulmonary embolism • Active bleeding or risk of >100 ml blood loss • Hematological disorder/malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference in hemoglobin level between upright and supine position in the same patient. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other study parameters are albumin and uric acid before and after mobilisation in chair. | — |
Countries
Netherlands