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The use of a blood transfer device to improve venous blood gas analysis

The use of a blood transfer device to improve venous blood gas analysis - Venous blood gas analysis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON56903
Enrollment
186
Registered
2024-07-29
Start date
2025-02-11
Completion date
Unknown
Last updated
2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patiënten voor wie een bloedgasanalyse is geïndiceerd Venous bloodgas

Interventions

None listed

Sponsors

Meander Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Hospitalized patients patients who require a bloodgas analysis

Exclusion criteria

Exclusion criteria: Patients younger than 18 years old and incompetent patients

Design outcomes

Primary

MeasureTime frame
The primary aim of this study is to optimize VBG sampling, by testing the accuracy of VBG results obtained through the use of a blood transfer device (BTD). We will evaluate a comprehensive set of blood gas results (pH, bicarbonate, pCO2, pO2, oxygen saturation, lactate, ionised calcium, sodium, chloride, potassium, haemoglobin, FCOHb, FMethHb) from a VBG samples collected via a BTD. We will compare VBG results collected in three different tubes methods by using the same blood draw from an IV line: 1) directly into a blood gas syringe (golden standard referred to as blood gas syringe) 2) into a heparin tube and subsequently transferred to a capillary (referred to as capillary VBG) 3) Into a dummy tube and subsequently transferred to a blood gas syringe via a BTD (referred to as adapter VBG).

Secondary

MeasureTime frame
1. Evaluate influence of a different tube sequence: according to the CLSI and NVKC, tubes should be drawn in a specific sequence as the sequence may influence results. According to this guideline, a VBG should be drawn first in the sequence. However, it would be more practical to take a VBG at the end. We will test whether taking a VBG at the end of the sequence would influence blood gas results. 2. Following the sequence, a conventional VBG is immediately drawn in a blood gas syringe, but it can also be taken from a heparinized tube and then transferred to a blood gas syringe. It is not clear what the effect of heparin is on blood gas results, wherefore it is currently taken in a tube without anticoagulation (dummy tube). However, the use of a heparinized tube will minimize the risk for in vitro blood clotting, that can interfere with results. 3. The effect of storage (room temperature or on ice), time-to analysis and transport (pneumatic tube) have not been adequately described.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)