fundamenteel neurowetenschappelijk onderzoek in gezonde volwassenen normal brain function
Conditions
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - Between 18-40 years of age; - The ability and agreement to provide informed consent in sound body and mind, and the ability to fulfil the study*s requirements
Exclusion criteria
Exclusion criteria: - Under 18 years of age; - The consumption of more than four alcoholic units or any recreational psychoactive drugs within 24 hours before participation; - A history of serious head trauma or brain surgery, or (close relatives with) epilepsy, convulsion, or seizure; - Any current episodes of psychiatric or neurological disorders; - Claustrophobia; - Current pregnancy; - Predisposition for fainting spells (syncope); - Hearing problems or ringing in the ears; - Implanted metal devices or large ferromagnetic fragments in the head or upper body (excluding dental wire), or jewellery/piercing that cannot be removed; - Use of a medical plaster that cannot or may not be taken off (e.g., nicotine plaster); - Use of (prescription) medication interacting with neuromodulation; - Skin disease or sensitivity at intended stimulation sites; - Calcifications in the brain in the acoustic path, see Chapter 6.4 of the C1 for a more elaborate explanation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| During the task, participants' responses will control a joystick whose movements will be recorded. These behavioural responses will be categorised based on in-session conditions and between-session stimulation conditions. This allows us to compare the difference in behavioural responses between each condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cortical changes in oxygen usage will be mapped using fMRI during task performance. With this, we can map oxygen usage in brain areas including the ones that were shown to be involved by previous studies such as the Amygdala, dACC. This activity can then be related to between-session stimulation conditions and within-session task conditions. In addition to this, we will also use measures of autonomic arousal during the sessions such as respiratory activity, heart rate and electrodermal activity. | — |
Countries
Netherlands
Outcome results
None listed