Complex congenital heart disease Congenital heart disease
Conditions
Interventions
Fetal CMR
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Antenatal diagnosis of significant aortic and/or pulmonary CHD, defined as requiring intervention within the first year of postnatal life. Informed consent provided by both parents. Gestational age >24 weeks. The optimal gestational age for fetal CMR currently lies between 30-34 weeks.
Exclusion criteria
Exclusion criteria: Maternal age <16 years. Inability to correctly inform parents about study due to language barrier or other factors. Contraindication to MRI (see Radiology department checklist).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To test feasibility of fetal CMR on the three available MRI vendors (Philips, Siemens, General Electric) in all academic centers in The Netherlands. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess diagnostic capacity of fetal CMR and the additive value to fetal echocardiography (at gestational age 20-24 weeks and 30-34 weeks) for correct antenatal diagnosis of significant aortic and/or pulmonary CHD (correct CHD diagnosis based on postnatal findings). | — |
Countries
Netherlands
Contacts
Public ContactR de Lange
Universitair Medisch Centrum Utrecht
Outcome results
None listed