Rapid detection of chronic polyneuropathy in patients with diabetes mellitus or chronic kidney failure

Rapid detection of chronic polyneuropathy in patients with diabetes mellitus or chronic kidney failure - DE SNAP study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56883

Enrollment

370

Registered

2024-07-12

Start date

2024-08-22

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(peripheral) neuropathy nerve disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age > 18 year and diagnosed with diagnosed with diabetes mellitus type 2 or type 1 for more than 10 year (fasting glucose >= 7.0 mmol/l or non-fasting glucose >= 11.0 mmol/l or use of any antidiabetics) and/or chronic kidney failure (eGFR

Exclusion criteria

Exclusion criteria: unable to fill in the symptom questionnaire (e.g. a language barrier or severe cognitive problems)

Design outcomes

Primary

Measure	Time frame
The main study parameter is the performance of the E-PSS expressed as area under the curve (AUC) and visualize this with a receiver operating characteristic (ROC) curve. Using the Youden*s J statistic we will determine the cut-off value with the best discrimination performance. We will evaluate the performance further with the sensitivity and specificity for this cut-off value.	—

Secondary

Measure	Time frame
Secondary objectives are: - the prevalence of polyneuropathy, - the proportion of underdiagnosed polyneuropathy - the prevalence of co-occurrence of risk factors - usage of neuropathic painkillers - the relationship between presence of polyneuropathy and severity, duration and treatment of the underlying disease	—

Countries

Netherlands

Outcome results