valvular heart diseases and aneurysms (or dilation of a blood vessel) heart valve abnormalities and aneurysms (or vessel dilation)
Conditions
Interventions
ClearSight fingercuff and EV1000Samsung smart watchHappitech smartphone applicatie
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - >18 years of age - informed consent - diagnosed with valvular heart disease, thoracic aortic aneurysm or heart failure for surgerical procedure or outpatient visit appointment - or scheduled for coronary artery bypass grafting with good left ventricular function.
Exclusion criteria
Exclusion criteria: Subjects of which the non-invasive blood pressure cannot be measured with the finger cuff according to the Instruction for Use of the CS/EV1000 system
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint of the study is to assess whether the non-invasive arterial pressure waveform measured at the finger level exhibits any distinctive morphological characteristics. In particular, analysis will be focused on the following characteristics: · Prolongation of the total duration of ejection: systolic phase of the reconstructed aortic pressure waveform · Prolongation of the systolic upstroke time· The slope of the pressure rise during systole: dP/dt · The presence and position of the anacrotic and dicrotic notches · Alterations of the shape of the pulse contour · Increase of time-constant of the diastolic phase of the waveform · The presence of the high-frequency components in the reconstructed aortic pressure waveform · Reduction in pulse pressure | — |
Secondary
| Measure | Time frame |
|---|---|
| - Differences in accuracy of the model between males and females - Differences in the accuracy of the model related to the cause of thoracic aortic aneurysm such as genetic or age related- To detect the existence of valvular heart disease based on the accessible and low cost photoplethysmogram (PPG) signal. | — |
Countries
Netherlands
Contacts
Public ContactD.P. Veelo
Amsterdam UMC
Outcome results
None listed