brain tumors cancer
Conditions
Interventions
None listed
Sponsors
Rijksuniversiteit Groningen
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Healthy sibling/control child: - Age between 4;0 and 15;11 years at the time of enrollment - Attend regular education In order to be eligible to participate in this study as a child survivor of a PPFT, a subject must meet all of the following criteria: - Age between 4;0 and 15;11 years at the time of enrollment - Diagnosed with a posterior fossa tumor - Referred to the UMCG proton therapy center for proton therapy treatment
Exclusion criteria
Exclusion criteria: • A diagnosis of Developmental Language Disorder (DLD, taalontwikkelingsstoornis), or suspected DLD (vermoeden van taalontwikkelingsstoornis of taalachterstand) preceding the onset of tumour-related symptoms • History of neurodevelopmental disorders unrelated to the brain tumor • History of psychiatric illness preceding the onset of tumour-related symptoms • Intellectual disability preceding the onset of tumour-related symptoms (determined by a certified professional) • Severe articulatory difficulties preceding the onset of tumour-related symptoms (determined by a certified professional) • Uncorrected vision or hearing impairment preceding the onset of tumour-related symptoms (determined by a certified professional)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For the behavioural data, the main study parameters are the scores on each of the language tests administered (e.g., sum of words/sentences correctly recalled/named/understood for each child). For MRI, the main parameters are white matter integrity and microstructure and grey matter thickness, volume and area. | — |
Secondary
| Measure | Time frame |
|---|---|
| N.A. | — |
Countries
Netherlands
Contacts
Public ContactV.M. De Aguiar
Rijksuniversiteit Groningen
Outcome results
None listed