Point-of-care ultrasound of optic nerve sheath diameter in suspected hypertensive emergency*

Point-of-care ultrasound of optic nerve sheath diameter in suspected hypertensive emergency* - OpticUS

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56796

Enrollment

400

Registered

2024-06-03

Start date

2024-10-21

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

swelling of the optic disc very high bloodpressure

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: >= 18 years old suspected hypertensive emergency

Exclusion criteria

Exclusion criteria: - Patients with preexisting optic nerve head changes such as glaucoma, pre-existing retinal artery/vein occlusions or any other condition that makes assessment of the fundi impossible. - Primary neurological cause of hypertension: ischemic cerebrovascular incident

Design outcomes

Primary

Measure	Time frame
The negative predictive value of ultrasonography of the ONSD for the diagnosis papilledema (grade 4 hypertensive retinopathy).	—

Secondary

Measure	Time frame
- Diagnostic characteristics of the ultrasonographic presence of bulging of the optic nerve head, crescent sign and/or decrease of ONSD with lateral eye movement for the diagnosis of papilledema. - Diagnostic characteristics of ultrasonography of the ONSD for the diagnosis of hypertensive encephalopathy - Diagnostic characteristics of ultrasonography of the ONSD for the need of intravenously administered rapid blood lowering medications - To evaluate the role of the ONSD measurement in the assessment of patients with suspected hypertensive emergency - The agreement between funduscopy findings and non-mydriatic ocular fundus photography findings	—

Measure

Time frame

- Diagnostic characteristics of the ultrasonographic presence of bulging of the optic nerve head, crescent sign and/or decrease of ONSD with lateral eye movement for the diagnosis of papilledema. - Diagnostic characteristics of ultrasonography of the ONSD for the diagnosis of hypertensive encephalopathy - Diagnostic characteristics of ultrasonography of the ONSD for the need of intravenously administered rapid blood lowering medications - To evaluate the role of the ONSD measurement in the assessment of patients with suspected hypertensive emergency - The agreement between funduscopy findings and non-mydriatic ocular fundus photography findings

—

Countries

Netherlands

Outcome results