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The (cost-)effectiveness of generalist (GIT-PD) versus specialist treatment (MBT/ST) for severe personality disorders (the P-DAET study): a pragmatic randomized controlled non-inferiority trial

The (cost-)effectiveness of generalist (GIT-PD) versus specialist treatment (MBT/ST) for severe personality disorders (the P-DAET study): a pragmatic randomized controlled non-inferiority trial - P-DAET

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON56791
Enrollment
358
Registered
2024-02-27
Start date
2024-10-21
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

personality problems character pathology

Interventions

There are 2 conditions in this study: 1) Participants receive a generalist treatment for personality problems, namely GIT-PD 2) Participants receive specialist treatment for personality problems, na

Sponsors

Arkin
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients (age 18 or older) who meet DSM-5 criteria for *severe* or *extreme* PD according to the alternative model for PDs, as assessed by the Semi-Structured Interview for Personality Functioning DSM-5 (STiP-5.1)

Exclusion criteria

Exclusion criteria: - Autism Spectrum Disorder - Chronic psychotic disorder - IQ

Design outcomes

Primary

MeasureTime frame
The level of personality functioning after 1.5 years of therapy and the difference between both conditions in terms of personality functioning

Secondary

MeasureTime frame
- Drop-out after randomization - Severity of symptoms - Psychosocial functioning - Costs - What works for whom? Determining different treatment effects between specialized treatments and generalist treatments (GIT-PD) by combining multiple predictors in an algorithm (the Personalized Advantage Index) and building a model to generate individual treatment recommendations.See research protocol for the specific predictors that will be measured.

Countries

Netherlands

Contacts

Public ContactCA Bomhof

Universiteit van Tilburg

c.a.bomhof@tilburguniversity.edu0657291504

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 3, 2026