Stroke, Cerebro vascular accident (CVA)
Conditions
Interventions
Participants will randomly be assigned to
• experimental group A - single training session with real perturbations,
immediately followed by 5 weeks of home-based HEROES exergame training
• experimental group B - single session with real pert
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Age between 18 and 75 years old. - Have sustained a unilateral supratentorial stroke more than 6 months ago. - Have completed the primary post-stroke rehabilitation treatment - Experiencing mild to moderate impairments in balance and walking. - Physically able to stand and walk independently (Functional Ambulation Categories score >=4). - Living in the community.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Conditions in which physical activity is contra-indicated. - Conditions in which reactive step training on the GRAIL is contra-indicated. - Any other neurological or musculoskeletal conditions affecting balance or gait abilities. - Impaired vision that is not corrected by glasses or lenses. - Severe cognitive problems based on the Montreal Cognitive Assessment. - Persistent visuo-spatial neglect based on the Star-Cancellation Test. - Use of psychotropic drugs or other medication negatively affecting balance. - Behavioural problems interfering with compliance to the study protocol. - Unable to use the intervention system independently. - Unable to give a personal informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the quality of the reactive stepping response following perturbations from standstill. The quality will be expressed as the angle of the stepping leg relative to the vertical at foot contact. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Multiple stepping threshold in the forward and backward direction. - Spatiotemporal step characteristic (step onset, step duration, step length and step velocity) and anticipatory step characteristics (forward lean and weight-bearing assymetry) at the multiple stepping threshold in the forward and backward direction, as these parameters have the potential to explain the presence or absence of differences in the primary outcome. - Clinical outcome measures (Fugl-Meyer Motor Assessment lower extremity subscale, Trunk Impairment Scale, Mini-BESTest, Functional Ambulation Category, 10-meter Walk Test, Dynamic Gait Index). This standardized core set of post stroke balance and mobility assessments will be performed according to the consensus-based recommendations from the Stroke Recovery and Rehabilitation Roundtable. | — |
Countries
Netherlands
Contacts
Public ContactLC Hagedoorn
Radboud Universitair Medisch Centrum
Outcome results
None listed